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Olli Ritvos Selected Research

Activin Receptors (Activin Receptor)

1/2020Systemic blockade of ACVR2B ligands attenuates muscle wasting in ischemic heart failure without compromising cardiac function.
11/2019Blocking Activin Receptor Ligands Is Not Sufficient to Rescue Cancer-Associated Gut Microbiota-A Role for Gut Microbial Flagellin in Colorectal Cancer and Cachexia?
1/2019Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade.
1/2019Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension.
1/2018Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses.
1/2018Activin Receptor Ligand Blocking and Cancer Have Distinct Effects on Protein and Redox Homeostasis in Skeletal Muscle and Liver.
12/2016Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.
10/2016Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.

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Olli Ritvos Research Topics

Disease

10Neoplasms (Cancer)
04/2020 - 03/2015
8Cachexia
01/2021 - 01/2018
5Hypertrophy
01/2021 - 09/2015
4COVID-19
01/2022 - 01/2021
4Fibrosis (Cirrhosis)
01/2021 - 02/2012
4Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
07/2020 - 12/2012
4Inflammation (Inflammations)
01/2020 - 03/2015
2Adenoma (Adenomas)
01/2021 - 05/2014
2Muscular Atrophy (Muscle Atrophy)
01/2021 - 01/2019
2Neuromuscular Diseases (Neuromuscular Disease)
04/2020 - 08/2014
2Malignant Mesothelioma
01/2020 - 03/2015
2Colorectal Neoplasms (Colorectal Cancer)
11/2019 - 05/2014
2Granulosa Cell Tumor
01/2017 - 03/2012
1Postmenopausal Osteoporosis
01/2022
1Pre-Eclampsia (Preeclampsia)
08/2021
1Reinfection
01/2021
1Atrophy
01/2021
1Cicatrix (Scar)
01/2021
1Coronavirus Infections
01/2021
1Seminoma
04/2020
1Sarcopenia
04/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2020
1Pancreatitis
01/2020
1Epidermolysis Bullosa
01/2020
1Wounds and Injuries (Trauma)
01/2020
1Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa)
01/2020
1Heart Failure
01/2020
1Metaplasia
01/2020
1Myocardial Infarction
01/2020
1Polyploidy
01/2019
1Right Ventricular Hypertrophy
01/2019
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2019
1Hypoxia (Hypoxemia)
01/2019
1Carcinoma (Carcinomatosis)
01/2019
1Reperfusion Injury
01/2019
1Pulmonary Hypertension
01/2019
1Pulmonary Arterial Hypertension
01/2019
1Osteoporosis
01/2019

Drug/Important Bio-Agent (IBA)

15LigandsIBA
01/2021 - 12/2015
14Proteins (Proteins, Gene)FDA Link
01/2021 - 02/2003
13Activins (Activin)IBA
01/2021 - 11/2014
9activin AIBA
01/2021 - 02/2012
8MyostatinIBA
01/2021 - 11/2003
8Activin Receptors (Activin Receptor)IBA
01/2020 - 10/2016
5FollistatinIBA
01/2021 - 11/2014
4Insulin (Novolin)FDA Link
01/2021 - 09/2015
4Transforming Growth Factors (Transforming Growth Factor)IBA
01/2021 - 12/2015
3Messenger RNA (mRNA)IBA
01/2022 - 01/2019
3activin BIBA
01/2021 - 11/2014
3Peptides (Polypeptides)IBA
01/2020 - 12/2002
2VaccinesIBA
01/2022 - 01/2021
2mRNA VaccinesIBA
01/2022 - 01/2021
2Immunoglobulin G (IgG)IBA
01/2021 - 11/2014
2AntigensIBA
01/2021 - 01/2017
2Insulin-Like Growth Factor I (IGF-1)IBA
01/2021 - 09/2015
2DystrophinIBA
07/2020 - 12/2012
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2019
2AntibodiesIBA
01/2019 - 11/2014
2Endoplasmic Reticulum Chaperone BiPIBA
01/2018 - 10/2016
2inhibin BIBA
01/2017 - 03/2012
1Neutralizing AntibodiesIBA
01/2022
1BNT162 VaccineIBA
01/2022
12019-nCoV Vaccine mRNA-1273IBA
01/2022
1Pregnancy-Associated Plasma Protein-A (PAPP-A)IBA
08/2021
1inhibin AIBA
08/2021
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2021
1RNA (Ribonucleic Acid)IBA
01/2021
1activin receptor type II-BIBA
01/2021
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2021
1CollagenIBA
01/2021
1EnzymesIBA
01/2021
1Histone Deacetylases (Histone Deacetylase)IBA
01/2021
1Immunoglobulin A (IgA)IBA
01/2021
1Immunoglobulin IsotypesIBA
01/2021
1NucleoproteinsIBA
01/2021
1Transforming Growth Factor beta (TGF-beta)IBA
01/2021
1p21-Activated KinasesIBA
01/2021
1Pharmaceutical PreparationsIBA
01/2020
1PlatinumIBA
01/2020
1FlagellinIBA
11/2019
1Interleukin-6 (Interleukin 6)IBA
11/2019
1Endothelin-1 (Endothelin 1)IBA
01/2019
1MonocrotalineIBA
01/2019
1pyrimidineIBA
01/2019
1Ribosomal RNAIBA
01/2019
1AdrenomedullinIBA
01/2019
1Vasodilator Agents (Vasodilators)IBA
01/2019
1Vasoconstrictor AgentsIBA
01/2019
1Bone Morphogenetic Protein ReceptorsIBA
01/2019
1ApelinIBA
01/2019
1Growth Differentiation Factor 2IBA
01/2019
1NucleotidesIBA
01/2019
1Amino AcidsFDA Link
01/2019
1Phenylalanine (L-Phenylalanine)FDA Link
01/2019
1Phosphates (Orthophosphate)IBA
01/2019
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2019
1Sirolimus (Rapamycin)FDA Link
01/2018

Therapy/Procedure

3Therapeutics
01/2021 - 08/2014
2Drug Therapy (Chemotherapy)
01/2020 - 01/2018
1Ovariectomy (Oophorectomy)
01/2022